CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27498
Family Name Acyl-CoA:cholesterol acyltransferase inhibitor SureCN13328411 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00482923 Functional Category Bioactive
Superfamily Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransferase 1 Binder Superfamily 3
Class Class 4235

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
Motilin receptor Ligand GSK962040 Family 30 457
Androgen receptor Ligand YM-175735 Family 30 129
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16
Sterol O-acyltransferase 1 inhibitor SureCN7565101 family 2 10
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9352718 f... 2 3
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9614694 f... 3 14
Acyl-CoA:cholesterol acyltransferase inhibitor tetradecan-2-yl... 2 4
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 2 0
Acyl-CoA:cholesterol acyltransferase inhibitor N-[2,6-di(propa... 1 2
Acyl-CoA:cholesterol acyltransferase inhibitor N-[[2,6-di(prop... 1 0
Sterol O-acyltransferase 1 inhibitor SureCN9848375 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00482927 CHEMBL46534 Bioactive SureCN9818663
CFAMM00482926 CHEMBL295671 Bioactive SureCN13328413
CFAMM00482924 CHEMBL294984 Bioactive 2-[2-acetyloxyethyl-[[3-[1-[[[2,6-di(propan-2-yl)phenyl]carbamoylamino]methyl]cyclopentyl]phenyl]methyl]amino]ethyl acetate
CFAMM00482923 CHEMBL44435 Bioactive SureCN13328411

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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