CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27534
Family Name Reverse transcriptase/RNaseH inhibitor 7CN-6Et-9Me-PBOA-5one family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00483081 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Prelamin-A/C Binder Superfamily
Class Class 2593

Cousin Family NamesSeedsMembers
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Motilin receptor ligand SureCN2768193 family 2 1
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(6-amino-... 1 2
Reverse transcriptase/RNaseH inhibitor 6Et-9Me-7NO2-PBOA-5one ... 2 5
Reverse transcriptase/RNaseH inhibitor 3Am-6Et-7,9-diMe-PBOA-5... 4 1
Reverse transcriptase/RNaseH inhibitor 2Cl-5MeSEt-PBOA-6one fa... 1 1
NP N-(2-(2-methoxyphenyl)-4-oxo-4h-chromen-6-yl)nicotinamide F... 9 0


External ID

Functional Category

Molecule Name

CFAMM00483081 CHEMBL55445 Bioactive 7CN-6Et-9Me-PBOA-5one
CFAMM00483080 CHEMBL56052 Bioactive 7CN-6,9-diMe-PBOA-5one
CFAMM00483079 CHEMBL440860 Bioactive 6Et-7,9-diMe-PBOA-5one
CFAMM00483083 CHEMBL298607 Bioactive 7MeOCO-6,9-diMe-PBOA-5one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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