CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27535
Family Name Proto-oncogene tyrosine-protein kinase Src and Fibroblast growth factor receptor 1 ligand 6-arylpyrido[2,3-d]pyrimidine deriv. 69 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00483085 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Glucagon receptor Binder Superfamily
Class Class 1049

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
MK-6096 family 3 69
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
Dihydrofolate reductase inhibitor AC1L9XPA family 6 5
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6 12
Vascular endothelial growth factor receptor 2 ligand 1-[4-[6-a... 11 13
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Corticotropin-releasing factor receptor 1 ligand AGN-PC-009TSL... 3 3
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 6 13
Melanocortin receptor 4 ligand N-[(2R)-3-(2,4-dichlorophenyl)-... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 18 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 1
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Dihydrofolate reductase inhibitor AC1LAPW3 family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483085 CHEMBL298679 Bioactive 6-arylpyrido[2,3-d]pyrimidine deriv. 69
CFAMM00483084 CHEMBL60979 Bioactive 6-arylpyrido[2,3-d]pyrimidine deriv. 68

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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