CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27539
Family Name 5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine receptor 3D ligand CHEMBL299097 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00483101 Functional Category Bioactive
Superfamily Cytochrome P450 2C9 and Cytochrome P450 3A4 Binder Superfamily 4
Class Class 2102

Cousin Family NamesSeedsMembers
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Transient receptor potential cation channel subfamily V member... 15 457
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
PF-4217903 family 14 65
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Aromatase and Thromboxane-A synthase Inhibitor 6-(1h-imidazol-... 3 8
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Metabotropic glutamate receptor 5 Ligand 2-m-tolyl-1,8-naphthy... 7 11
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Aromatase Inhibitor NSC-356781 Family 3 10
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... 3 10
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 4 2
Platelet-activating factor receptor ligand AGN-PC-0750SP family 4 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Type-1B angiotensin II receptor ligand SureCN683399 family 3 0
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Transient receptor potential cation channel subfamily V member... 4 0
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483101 CHEMBL299097 Bioactive CHEMBL299097

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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