CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27542
Family Name Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 inhibitor N-[(2S)-1-anilino-1-oxo-3-phenylpropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00483128 Functional Category Bioactive
Superfamily Metalloproteinase and Matrix metalloproteinase-9 Binder Superfamily
Class Class 349

Cousin Family NamesSeedsMembers
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 9 43
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 6 4
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 1 3
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 1 0


External ID

Functional Category

Molecule Name

CFAMM00483125 CHEMBL60195 Bioactive N-[(2S)-1-(4-chloroanilino)-1-oxo-3-phenylpropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00483123 CHEMBL417383 Bioactive 4-ethoxy-N-[(2S)-1-(4-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00483122 CHEMBL299265 Bioactive N-[(2S)-1-[4-(dimethylamino)anilino]-1-oxo-3-phenylpropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00483128 CHEMBL59496 Bioactive N-[(2S)-1-anilino-1-oxo-3-phenylpropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00483127 CHEMBL64069 Bioactive N-[(2S)-1-anilino-3-(4-chlorophenyl)-1-oxopropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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