CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27586
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2A ligand AGN-PC-00LF5H family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00483331 Functional Category Bioactive
Superfamily Voltage-dependent L-type calcium channel subunit alpha-1C and Voltage-dependent L-type calcium channel subunit alpha-1D Binder Superfamily 2
Class Class 2018

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor alpha and Platelet-der... 6 8
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
Leukotriene A-4 hydrolase Inhibitor 2-(4-piperidin-1-ylmethylp... 5 47
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 2
Neuropeptide Y receptor type 1 ligand SureCN7959923 family 1 6
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 3 10
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
C5a anaphylatoxin chemotactic receptor 1 ligand 2-(2,6-diethyl... 3 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 4 3
Cholinesterase and Acetylcholinesterase inhibitor N-[6-[4-(1,3... 1 0
Prostaglandin G/H synthase 1 and Cytochrome P450 3A4 inhibitor... 1 3
Beta-lactamase and Muscleblind-like protein 1 inhibitor 2,3-Bi... 1 2


External ID

Functional Category

Molecule Name

CFAMM00483329 CHEMBL304016 Bioactive 2-(6,7-dihydro-[1]benzoxepino[4,5-c]quinolin-8-ylsulfanyl)-N,N-dimethylethanamine
CFAMM00483323 CHEMBL305907 Bioactive AGN-PC-0002RA
CFAMM00483331 CHEMBL543825 Bioactive AGN-PC-00LF5H

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



60387 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543