CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2761
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2C ligand 3-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-5,5-dimethyl-1,3-thiazolidin-4-one family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00337669 Functional Category Bioactive
Superfamily Prelamin-A/C and Substance-P receptor Binder Superfamily 2
Class Class 2519

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 19 88
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
5-hydroxytryptamine receptor 2A Ligand Cinanserin Family 3 27
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Amine oxidase [flavin-containing] B Inhibitor L-136662 Family 3 20
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 5
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 18 12
Androgen receptor ligand CHEMBL182412 family 2 8
5-hydroxytryptamine receptor 1A ligand SureCN4244417 family 10 1
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 2
Cannabinoid receptor 2 ligand 1-adamantyl-(5-fluoro-2,3-dihydr... 4 7
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Somatostatin receptor type 1 ligand AGN-PC-078XL6 family 9 9
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00337669 CHEMBL130290 Bioactive 3-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-5,5-dimethyl-1,3-thiazolidin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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