CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27612
Family Name Calpain-1 catalytic subunit inhibitor 2,5-dichloro-N-[(2S)-3,4-dioxo-1-phenyl-4-[2-[(5-pyridin-2-ylthiophen-2-yl)sulfonylamino]ethylamino]butan-2-yl]benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00483396 Functional Category Bioactive
Superfamily Calpain-1 catalytic subunit Binder Superfamily 2
Class Class 2076

Cousin Family NamesSeedsMembers
Integrin beta-3 Inhibitor L-739758 Family 2 4
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-073U... 3 8
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 4
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 10 14
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 4 1
Calpain-1 catalytic subunit inhibitor (3S)-3-[[(2R)-2-(methane... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483397 CHEMBL310826 Bioactive 2,6-dichloro-N-[(2S)-3,4-dioxo-1-phenyl-4-[2-[(5-pyridin-2-ylthiophen-2-yl)sulfonylamino]ethylamino]butan-2-yl]benzamide
CFAMM00483396 CHEMBL306616 Bioactive 2,5-dichloro-N-[(2S)-3,4-dioxo-1-phenyl-4-[2-[(5-pyridin-2-ylthiophen-2-yl)sulfonylamino]ethylamino]butan-2-yl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27509 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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