CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27623
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 1-cyclopentyl-3-ethyl-6-(3-methoxyphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00483437 Functional Category Bioactive
Superfamily C-C chemokine receptor type 1 and Cytochrome P450 2C19 Binder Superfamily
Class Class 4713

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Family 13 41
Coagulation factor X Inhibitor Apixaban Family 34 52
5-hydroxytryptamine receptor 3A ligand 1-[4-[[7-(diethylamino)... 2 4
5-hydroxytryptamine receptor 3A ligand 5-hydroxy-1-methyl-N-[(... 4 2
Coagulation factor X inhibitor SureCN6785555 family 7 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 7-met... 2 1
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-(3-me... 2 10
Coagulation factor X inhibitor AGN-PC-077MYE family 16 0
Coagulation factor X inhibitor SureCN5644036 family 30 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483438 CHEMBL76066 Bioactive SureCN7376577
CFAMM00483437 CHEMBL307678 Bioactive 1-cyclopentyl-3-ethyl-6-(3-methoxyphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27298 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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