CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27669
Family Name Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9057529 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00483598 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform and Serine/threonine-protein kinase mTOR Inhibitor BEZ235 Superfamily
Class Class 147

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 12 108
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 10 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 5 11
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 5 0
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 0
Acyl-CoA:cholesterol acyltransferase inhibitor AGN-PC-00GCQW f... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483599 CHEMBL78597 Bioactive 1-cycloheptyl-1-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-3-(2,4,6-trimethylphenyl)urea
CFAMM00483598 CHEMBL311193 Bioactive SureCN9057529

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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