CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27673
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor 4-(8-chloro-5H-[1]benzothiepino[4,3-b]pyridin-11-ylidene)-N-cyano-N'-(pyridin-4-ylmethyl)piperidine-1-carboximidamide family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00483613 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 21
Class Class 72

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483610 CHEMBL313090 Bioactive AGN-PC-040RLA
CFAMM00483615 CHEMBL311434 Bioactive 4-(8-chloro-5H-[1]benzothiepino[4,3-b]pyridin-11-ylidene)-N-cyano-N'-[(1-oxidopyridin-1-ium-3-yl)methyl]piperidine-1-carboximidamide
CFAMM00483613 CHEMBL81889 Bioactive 4-(8-chloro-5H-[1]benzothiepino[4,3-b]pyridin-11-ylidene)-N-cyano-N'-(pyridin-4-ylmethyl)piperidine-1-carboximidamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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