CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM277
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor AGN-PC-00A0KS family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00150466 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and Transporter Binder Superfamily
Class Class 1028

Cousin Family NamesSeedsMembers
Calmodulin inhibitor phenothiazine derivative Trifluoperazine ... 3 30
Muscarinic acetylcholine receptor M5 ligand phenothiazine deri... 8 37
Alpha-1B adrenergic receptor Ligand Propericiazine Family 2 0
Histamine H1 receptor ligand phenothiazine derivative Mequitaz... 3 2
Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
5-hydroxytryptamine receptor Ligand Lu AA21004 Family 13 39
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 2A Ligand Cinanserin Family 3 27
Sodium-dependent serotonin transporter and Sodium-dependent do... 4 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-075CMN family 2 1
Sodium-dependent serotonin transporter and Transporter inhibit... 4 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 4 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 4 1
5-hydroxytryptamine receptor 1A ligand AGN-PC-00JBJI family 1 1
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
5-hydroxytryptamine receptor 6 ligand SureCN10040111 family 1 3
Amine oxidase [flavin-containing] A inhibitor SureCN5111868 fa... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00309735 CHEMBL245915 Bioactive AGN-PC-046EQM
CFAMM00309734 CHEMBL246120 Bioactive 3-amino-4-[2-[(dimethylamino)methyl]-4-fluorophenyl]sulfanylbenzonitrile
CFAMM00309732 CHEMBL106939 Bioactive DASB
CFAMM00309736 CHEMBL203821 Bioactive 2-[2-[(dimethylamino)methyl]phenyl]sulfinyl-5-methylaniline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25040 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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