CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27725
Family Name Reverse transcriptase/RNaseH inhibitor (R)-(+)9B-(3-METHYL)PHENYL-2,3-DIHYDROTHIAZOLO[2,3-A]ISOINDOL-5(9BH)-ONE family
No. of Seeds 5 No. of Other Members 24
Family Centroid CFAMM00483817 Functional Category Bioactive with Natural Product
Superfamily 72 kDa type IV collagenase and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3514

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
DNA Binder Procarbazine Family 8 358
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 2 23
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Pol polyprotein inhibitor penicillin deriv. 34 family 3 18
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 5 3
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075C6K ... 3 22
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 3 9
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 1 162
5-hydroxytryptamine receptor 1A and Alpha-2B adrenergic recept... 2 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Prolyl endopeptidase and Seprase inhibitor [(2R)-1-[2-[benzoyl... 2 0
Pol polyprotein inhibitor penicillin deriv. 43 family 2 1
C-C chemokine receptor type 5 ligand N-benzyl-N-[(3R)-1-[(1S,5... 1 3
Retinal dehydrogenase 1 and 15-hydroxyprostaglandin dehydrogen... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 1 5
Histone deacetylase 6 and Histone deacetylase 1 inhibitor AGN-... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483805 CHEMBL84900 Bioactive AC1L9SCO
CFAMM00483825 CHEMBL83632 Bioactive AC1L9SCR
CFAMM00483824 CHEMBL315289 Bioactive BM 51.0836
CFAMM00483817 CHEMBL430639 Bioactive (R)-(+)9B-(3-METHYL)PHENYL-2,3-DIHYDROTHIAZOLO[2,3-A]ISOINDOL-5(9BH)-ONE
CFAMM00483806 CHEMBL85446 Bioactive 9b-(3-Methylphenyl)-2,3-dihydrothiazolo[2,3-a]isoindol-5(9bH)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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