CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27736
Family Name Arachidonate 5-lipoxygenase inhibitor 4-(furan-3-yl)-7-[[5-(4-hydroxyoxan-4-yl)pyridin-3-yl]methoxy]naphthalene-2-carbonitrile family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00483856 Functional Category Bioactive
Superfamily Beta-lactamase and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 4855

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Leukotriene B4 receptor 1 ligand AGN-PC-04XM3V family 3 10
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Serine/threonine-protein kinase B-raf inhibitor furan-based co... 6 3
Arachidonate 5-lipoxygenase inhibitor 7-[[3-fluoro-5-(1-hydrox... 1 0
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00483858 CHEMBL99217 Bioactive AGN-PC-00GCJH
CFAMM00483856 CHEMBL316641 Bioactive 4-(furan-3-yl)-7-[[5-(4-hydroxyoxan-4-yl)pyridin-3-yl]methoxy]naphthalene-2-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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