CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27798
Family Name DNA topoisomerase 2-alpha and DNA topoisomerase 2-beta inhibitor [3-(acridin-9-ylamino)-5-(methanesulfonamido)phenyl]methyl acetate family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00484046 Functional Category Bioactive
Superfamily DNA topoisomerase 2-beta and DNA topoisomerase 2-alpha Binder Superfamily 2
Class Class 70

Cousin Family NamesSeedsMembers
Food vacuoles Inhibitor Mefloquine Family 2 25
Acetylcholinesterase Inhibitor Velnacrine Family 2 29
Metabotropic glutamate receptor 5 Ligand (3-(2-methylquinolin-... 3 6
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8


External ID

Functional Category

Molecule Name

CFAMM00484046 CHEMBL325543 Bioactive [3-(acridin-9-ylamino)-5-(methanesulfonamido)phenyl]methyl acetate
CFAMM00484039 CHEMBL326664 Bioactive N-[3-(acridin-9-ylamino)-5-(hydroxymethyl)phenyl]methanesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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