CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27826
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor 7-(5-hydroxypentyl)-1,3-dihydroimidazo[4,5-b]quinolin-2-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00484158 Functional Category Bioactive
Superfamily cGMP-inhibited 3',5'-cyclic phosphodiesterase A and cGMP-inhibited 3',5'-cyclic phosphodiesterase B Binder Superfamily
Class Class 969

Cousin Family NamesSeedsMembers
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 5 2
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5


External ID

Functional Category

Molecule Name

CFAMM00484158 CHEMBL328755 Bioactive 7-(5-hydroxypentyl)-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00484157 CHEMBL88224 Bioactive 7-(3-hydroxypropyl)-1,3-dihydroimidazo[4,5-b]quinolin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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