CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2785
Family Name Acetylcholinesterase and Butyrylcholinesterase inhibitor N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-benzylsulfonyl-N-methylbenzamide family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00337860 Functional Category Bioactive
Superfamily Acetylcholinesterase and Butyrylcholinesterase Binder Superfamily
Class Class 2586

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Muscarinic acetylcholine receptor M2 Ligand SCH-211803 Family 3 6
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 7 8
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 1 14
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-3-methyl-... 3 4
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745OU family 6 6
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 1
Thyroid hormone receptor beta ligand CHEMBL1593113 family 1 4
Acetylcholinesterase inhibitor N-[2-(1-benzylpiperidin-4-yl)et... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 5
C-C chemokine receptor type 5 ligand AGN-PC-075XOD family 2 0
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
C-C chemokine receptor type 5 ligand N-[1-[(3R)-4-[benzenesulf... 3 1
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 5 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00337860 CHEMBL299708 Bioactive N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-benzylsulfonyl-N-methylbenzamide
CFAMM00337857 CHEMBL56960 Bioactive Piperidine Derivative 22
CFAMM00337853 CHEMBL542744 Bioactive 1-Benzyl-4-(2-(N-(4'-(benzylsulfonyl)benzoyl)-N-methylamino)ethyl)piperidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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