CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27866
Family Name Pol polyprotein inhibitor (2R,4S)-N-[(2S)-3-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-2-hydroxypropyl]-2-[2-[[4-(dimethylamino)phenyl]methylamino]-2-oxo-1-[(2-phenylacetyl)amino]ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00484271 Functional Category Bioactive
Superfamily Caspase-3 and Pol polyprotein Binder Superfamily
Class Class 2064

Cousin Family NamesSeedsMembers
Pol polyprotein inhibitor penicillin deriv. 49 family 3 19
Pol polyprotein inhibitor penicillin deriv. 69 family 1 1
Pol polyprotein inhibitor Sulfone deriv. 31 family 15 4
Pol polyprotein inhibitor AC1LACBC family 2 0


External ID

Functional Category

Molecule Name

CFAMM00484271 CHEMBL333982 Bioactive (2R,4S)-N-[(2S)-3-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-2-hydroxypropyl]-2-[2-[[4-(dimethylamino)phenyl]methylamino]-2-oxo-1-[(2-phenylacetyl)amino]ethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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