CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27873
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL335148 family
No. of Seeds 1 No. of Other Members 9
Family Centroid CFAMM00484291 Functional Category Bioactive with Natural Product
Superfamily Nuclear receptor ROR-gamma and Microtubule-associated protein tau Binder Superfamily 6
Class Class 2076

Cousin Family NamesSeedsMembers
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Growth hormone receptor Ligand EP-51216 Family 34 390
Lethal factor Inhibitor GM6001 Family 50 435
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 2 14
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Calcitonin gene-related peptide type 1 receptor ligand CHEMBL1... 5 8
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 17 28
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 1 0
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
5-hydroxytryptamine receptor 1A ligand 2-[4-(quinolin-2-ylmeth... 2 91
Nuclear receptor ROR-gamma and Niemann-Pick C1 protein ligand ... 1 12
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
Survival motor neuron protein and Menin inhibitor CHEMBL151109... 1 11
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
Serine/threonine-protein kinase D3 and Protein kinase C delta ... 3 10
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Neuromedin-K receptor ligand 3-methylsulfinyl-N-[(1S)-1-phenyl... 3 5
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 1
Adenosine receptor A2b and Adenosine receptor A2a ligand N-(4-... 2 14
Endothelin-1 receptor and Endothelin B receptor ligand 2-[[(2R... 5 3
Somatostatin receptor type 4 and Somatostatin receptor type 5 ... 3 4
5-hydroxytryptamine receptor 7 ligand AGN-PC-00PFK0 family 1 0
Interstitial collagenase and Matrix metalloproteinase-9 inhibi... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00484291 CHEMBL335148 Bioactive CHEMBL335148

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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