CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27880
Family Name Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransferase 1 inhibitor SureCN3378259 family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00484308 Functional Category Bioactive
Superfamily Ras-related protein Rab-9A and Prelamin-A/C Binder Superfamily
Class Class 169

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... 3 18
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 12
Sterol O-acyltransferase 1 inhibitor 1-(2,4-difluorophenyl)-3-... 8 90
Adenosine receptor A3 ligand 5-butyl-8-(4-methylsulfanylphenyl... 2 4
DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... 2 10
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Mitogen-activated protein kinase 14 inhibitor imidazole 81 family 2 1
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
Histamine H3 receptor ligand 5-(3-bromophenyl)-2-[2-(1H-imidaz... 2 2
Sterol O-acyltransferase 1 inhibitor AGN-PC-025JYX family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00484311 CHEMBL434418 Bioactive AGN-PC-075MQZ
CFAMM00484309 CHEMBL33780 Bioactive SureCN3379092
CFAMM00484308 CHEMBL33661 Bioactive SureCN3378259

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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