CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27893
Family Name Cathepsin K inhibitor benzyl N-[(2S)-4-methyl-1-oxo-1-[2-[[(4-phenylmethoxybenzoyl)amino]carbamoyl]hydrazinyl]pentan-2-yl]carbamate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00484339 Functional Category Bioactive
Superfamily Cathepsin K inhibitor benzyl N-[(2S)-4-methyl-1-oxo-1-[2-[[(4-phenylmethoxybenzoyl)amino]carbamoyl]hydrazinyl]pentan-2-yl]carbamate Superfamily
Class Class 3631

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand A-317920 Family 9 240
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 2 2
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-lle-agly-ile-v... 17 7
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-nal-agly-ile-v... 3 2
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0
Histamine H3 receptor and Cytochrome P450 2D6 ligand ethyl 4-[... 5 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00484339 CHEMBL338150 Bioactive benzyl N-[(2S)-4-methyl-1-oxo-1-[2-[[(4-phenylmethoxybenzoyl)amino]carbamoyl]hydrazinyl]pentan-2-yl]carbamate
CFAMM00484338 CHEMBL340191 Bioactive benzyl N-[(2S)-4-methyl-1-oxo-1-[2-[[(3-phenylmethoxybenzoyl)amino]carbamoyl]hydrazinyl]pentan-2-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543