CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27935
Family Name Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3,3-dimethyl-2-(thiophen-3-ylmethylamino)butan-1-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00484463 Functional Category Bioactive
Superfamily Orexin receptor type 2 and Orexin receptor type 1 Binder Superfamily 3
Class Class 3612

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
DNA-(apurinic or apyrimidinic site) lyase and Menin inhibitor ... 1 6
Mu-type opioid receptor ligand AGN-PC-075GCP family 2 8
Histamine H3 receptor ligand SureCN5093846 family 2 3
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00484462 CHEMBL344622 Bioactive (2S)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3,3-dimethyl-2-(thiophen-2-ylmethylamino)butan-1-one
CFAMM00484463 CHEMBL343786 Bioactive (2S)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3,3-dimethyl-2-(thiophen-3-ylmethylamino)butan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26400 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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