CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27985
Family Name Carbonic anhydrase 2 inhibitor 6-hydroxy-1H-indole-2-sulfonamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00484577 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 Binder Superfamily 11
Class Class 44

Cousin Family NamesSeedsMembers
Apricoxib family 8 77
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Plasminogen and Prothrombin Inhibitor 2-(2-hydroxy-phenyl)-1h-... 3 69
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
Carbonic anhydrase 2 inhibitor (2-sulfamoyl-1H-indol-6-yl) ace... 2 0
Carbonic anhydrase 4 and Carbonic anhydrase 2 inhibitor 5,10-d... 3 1
Proto-oncogene tyrosine-protein kinase Src and cAMP-dependent ... 2 0


External ID

Functional Category

Molecule Name

CFAMM00484577 CHEMBL350086 Bioactive 6-hydroxy-1H-indole-2-sulfonamide
CFAMM00484576 CHEMBL354238 Bioactive 5-hydroxy-1H-indole-2-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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