CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28015
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand 4-[2-[(3R,5R,10S,13S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]ethynyl]benzonitrile family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00484632 Functional Category Bioactive with Natural Product
Superfamily Bay 86-5044 Superfamily
Class Class 1063

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Bay 86-5044 family 2 17
Macrophage migration inhibitory factor Inhibitor 3,3,3-tris(4-... 4 16
DNA polymerase Inhibitor 3-cis-p-coumaroyl Maslinic Acid Family 3 38
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[9-... 2 15
Bile acid receptor ligand benzyl (1R,3aS,5aR,5bR,7aR,9S,11aR,1... 1 21
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00484634 CHEMBL83714 Bioactive (3R,10S,13S)-3-benzyl-3-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-one
CFAMM00484632 CHEMBL354688 Bioactive 4-[2-[(3R,5R,10S,13S,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]ethynyl]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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