CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28030
Family Name 5-hydroxytryptamine receptor 1A ligand (1S,5R)-8-[[(3S)-5-methoxy-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-3-pyridin-2-yl-8-azabicyclo[3.2.1]octan-3-ol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00484672 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Ligand SLV-313 Superfamily
Class Class 284

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Hemoglobin subunit alpha Inhibitor 4-[(5-methoxy-2-methylpheno... 3 12
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 1 1
Sodium-dependent serotonin transporter and Alpha-2C adrenergic... 2 2
Small conductance calcium-activated potassium channel protein ... 2 2


External ID

Functional Category

Molecule Name

CFAMM00484672 CHEMBL355953 Bioactive (1S,5R)-8-[[(3S)-5-methoxy-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-3-pyridin-2-yl-8-azabicyclo[3.2.1]octan-3-ol
CFAMM00484671 CHEMBL357985 Bioactive (1S,5R)-8-[[(3S)-5-ethoxy-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-3-pyridin-2-yl-8-azabicyclo[3.2.1]octan-3-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



27525 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543