CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28056
Family Name Receptor tyrosine-protein kinase erbB-2 and Epidermal growth factor receptor ligand (E)-N-[4-[3-chloro-4-[(4-phenyl-1,3-thiazol-2-yl)methyl]anilino]-3-cyano-7-methoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00484718 Functional Category Bioactive
Superfamily Atypical chemokine receptor 3 and Epidermal growth factor receptor Binder Superfamily
Class Class 2018

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor and Receptor tyrosine-protein... 16 89
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
Dual specificity mitogen-activated protein kinase kinase 1 inh... 5 7
Proto-oncogene tyrosine-protein kinase Src inhibitor AGN-PC-07... 17 9
Macrophage colony-stimulating factor 1 receptor ligand 4-(2,3-... 12 7


External ID

Functional Category

Molecule Name

CFAMM00484718 CHEMBL360979 Bioactive (E)-N-[4-[3-chloro-4-[(4-phenyl-1,3-thiazol-2-yl)methyl]anilino]-3-cyano-7-methoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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