CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28109
Family Name 5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic receptor ligand 1-(4-fluorophenyl)-4-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)piperazin-1-yl]butan-1-one family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00484884 Functional Category Bioactive
Superfamily Substance-P receptor and Alpha-1A adrenergic receptor Binder Superfamily 2
Class Class 2294

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
DNA Binder Procarbazine Family 8 358
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Substance-P receptor Ligand Orvepitant Family 11 46
Bavisant family 9 65
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Poly [ADP-ribose] polymerase 1 Inhibitor 3,4-dihydro-5-methyl-... 3 2
Farnesyltransferase beta subunit, putative and Protein farnesy... 6 3
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 4 10
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Substance-P receptor ligand AGN-PC-00FJ8P family 6 10
C-C chemokine receptor type 5 ligand AC1L9USC family 3 2
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Substance-P receptor ligand 3-[bis(4-fluorophenyl)methyl]-1-[[... 2 10
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
5-hydroxytryptamine receptor 1A ligand [(7S,8R)-7-(dipropylami... 4 0
Muscarinic acetylcholine receptor M3 ligand N-[[4-fluoro-3-[3-... 3 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TEL... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00484884 CHEMBL366388 Bioactive 1-(4-fluorophenyl)-4-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)piperazin-1-yl]butan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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