CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28126
Family Name Cellular tumor antigen p53 and E3 ubiquitin-protein ligase Mdm2 inhibitor (2S)-2-(4-chlorophenyl)-2-[(3S)-7-iodo-2,5-dioxo-3-[4-(trifluoromethoxy)phenyl]-1,3-dihydro-1,4-benzodiazepin-4-yl]acetic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00484943 Functional Category Bioactive
Superfamily Cellular tumor antigen p53 and Nuclear receptor ROR-gamma Binder Superfamily 2
Class Class 2065

Cousin Family NamesSeedsMembers
E3 ubiquitin-protein ligase Mdm2 inhibitor methyl 2-(4-chlorop... 2 8


External ID

Functional Category

Molecule Name

CFAMM00484943 CHEMBL369560 Bioactive (2S)-2-(4-chlorophenyl)-2-[(3S)-7-iodo-2,5-dioxo-3-[4-(trifluoromethoxy)phenyl]-1,3-dihydro-1,4-benzodiazepin-4-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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