CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28148
Family Name Adenosine receptor A2b and Adenosine receptor A1 ligand 8-[1-[[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]methyl]pyrazol-4-yl]-1,3-dipropyl-7H-purine-2,6-dione family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00484998 Functional Category Bioactive
Superfamily Insulin-like growth factor 1 receptor and Tyrosine-protein kinase JAK2 Binder Superfamily
Class Class 974

Cousin Family NamesSeedsMembers
Coagulation factor IX and Coagulation factor X Inhibitor Razax... 22 34
Adenosine receptor A2b Ligand CVT-6694 Family 1 22
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
Aurora kinase A and Potassium voltage-gated channel subfamily ... 8 7
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QJGR family 3 13
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
Tyrosine-protein kinase JAK2 and Cytochrome P450 1A2 inhibitor... 1 0
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Adenosine receptor A2b and Adenosine receptor A1 ligand N-(3,4... 1 8
Adenosine receptor A2b and Adenosine receptor A1 ligand N-[(3Z... 2 2


External ID

Functional Category

Molecule Name

CFAMM00484998 CHEMBL371649 Bioactive 8-[1-[[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]methyl]pyrazol-4-yl]-1,3-dipropyl-7H-purine-2,6-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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