CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28208
Family Name P2X purinoceptor 7 inhibitor 3-[[5-(2,3-dichlorophenyl)tetrazol-1-yl]methyl]-2-methylpyridine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00476244 Functional Category Bioactive
Superfamily Voltage-gated sodium channel ligand phenyltriazine analog Lamotrigine Superfamily
Class Class 37

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Adenosine receptor A3 and Adenosine receptor A2a ligand SureCN... 8 7
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Vasopressin V1a receptor ligand 2-[4-[4-[(3-chlorophenyl)methy... 1 0
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 3
P2X purinoceptor 7 inhibitor 3-[[1-[2-chloro-4-fluoro-3-(trifl... 2 0
P2X purinoceptor 7 inhibitor 1-benzyl-5-(2,3-dichlorophenyl)te... 2 6


External ID

Functional Category

Molecule Name

CFAMM00485157 CHEMBL427223 Bioactive 3-[[5-(2,3-dichloro-4-fluorophenyl)tetrazol-1-yl]methyl]pyridine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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