CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28214
Family Name Mitogen-activated protein kinase 14 inhibitor AGN-PC-00CRQ3 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00485175 Functional Category Bioactive
Superfamily Interleukin-6 and Interleukin-1 beta Binder Superfamily
Class Class 1101

Cousin Family NamesSeedsMembers
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Metabotropic glutamate receptor 5 Ligand N-(1,4-diphenyl-1h-py... 3 35
Metabotropic glutamate receptor 5 Ligand N-(1,3-diphenyl-1h-py... 6 37
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Mitogen-activated protein kinase kinase kinase kinase 5 and Du... 1 18
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor AGN-... 1 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Glucocorticoid receptor ligand 5-amino-N-[2-[(1-ethyl-3,4-dihy... 1 0
Glucocorticoid receptor ligand 5-amino-N-[(2R)-2-[[(2,6-dichlo... 6 5
Cyclin-dependent kinase 2 inhibitor N-[(4-chlorophenyl)carbamo... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485175 CHEMBL380755 Bioactive AGN-PC-00CRQ3

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48682 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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