CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28223
Family Name Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracyclic aza-amide, 10 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00485196 Functional Category Bioactive with Natural Product
Superfamily Peptidyl-prolyl cis-trans isomerase FKBP1A Binder Superfamily
Class Class 2276

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor 2-[3-[(1R... 9 46
Substance-P receptor ligand AGN-PC-075NSQ family 9 3
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 5 7
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-00... 5 14
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 1 5
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Cyclic az... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 1
NP (e)-4-methoxy-6,6-dimethyl-5-(2-oxo-4-(2,6,6-trimethylcyclo... 131 0
NP ((1r,4as,8as)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)octahydr... 3 3
Putative NP ZINC08791780 Family 3 0
2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485196 CHEMBL381637 Bioactive Tetracyclic aza-amide, 10

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26194 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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