CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28310
Family Name Histone deacetylase 1 and Histone deacetylase 2 inhibitor SureCN1067563 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00485362 Functional Category Bioactive
Superfamily Histone deacetylase 2 and Histone deacetylase 1 Binder Superfamily 10
Class Class 3553

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
Microsomal triglyceride transfer protein large subunit inhibit... 4 5
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Cathepsin L1 and Cathepsin S inhibitor arylaminoethyl amide, 5... 4 5
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-(3-methoxy-2-me... 2 4
Urokinase-type plasminogen activator and Trypsin-1 inhibitor A... 1 6
Leukotriene A-4 hydrolase inhibitor SureCN5313952 family 4 1
Histone deacetylase 1 and Histone deacetylase 2 inhibitor Sure... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485362 CHEMBL392747 Bioactive SureCN1067563
CFAMM00485361 CHEMBL400919 Bioactive AGN-PC-00R9FG

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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