CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28313
Family Name Histone deacetylase 1 inhibitor SureCN4538615 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00485371 Functional Category Bioactive
Superfamily P2Y purinoceptor 12 and Histone deacetylase 1 Binder Superfamily
Class Class 4009

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
XL-888 family 16 85
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cyclin-dependent kinase 4 Inhibitor 1-(9-oxo-9h-fluoren-4-yl)-... 3 5
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Histamine H3 receptor ligand 1-[1-[1-[(2-aminopyridin-4-yl)met... 16 9
Cellular tumor antigen p53 inhibitor CHEMBL1551403 family 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 22
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[[... 22 11
Protein kinase C theta type inhibitor (2-aminopyridin-3-yl)-[6... 4 1
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
ALK tyrosine kinase receptor ligand N-[6-[[4-(2-hydroxypropan-... 2 0
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Histamine H3 receptor ligand AGN-PC-075YVW family 1 2
Neutrophil elastase inhibitor AGN-PC-076VCN family 3 25
P2Y purinoceptor 12 inhibitor SureCN3925458 family 1 13
P2Y purinoceptor 12 inhibitor SureCN3928692 family 5 0
Corticotropin-releasing factor receptor 1 ligand AGN-PC-006EKH... 1 0
ethyl 4-[[(2S)-2-pyridin-3-ylpiperidine-1-carbothioyl]amino]be... 4 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485367 CHEMBL401026 Bioactive AGN-PC-0145SI
CFAMM00485371 CHEMBL393117 Bioactive SureCN4538615

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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