CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28321
Family Name Receptor tyrosine-protein kinase erbB-2 and Epidermal growth factor receptor ligand 2-[[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methoxy]acetic acid family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00485388 Functional Category Bioactive
Superfamily HER and Macrophage migration inhibitory factor Binder Superfamily
Class Class 860

Cousin Family NamesSeedsMembers
HER Inhibitor AC480 Family 4 67
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
PF-4217903 family 14 65
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 3
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
Mitogen-activated protein kinase 10 and Transcription factor A... 4 4
Serine/threonine-protein kinase mTOR inhibitor SureCN3776855 f... 1 0
Tyrosine-protein kinase JAK2 and ALK tyrosine kinase receptor ... 5 0
Mitogen-activated protein kinase 14 inhibitor methyl 4-[5-(eth... 3 11
Adenosine receptor A1 ligand N-butyl-5-phenyl-3-[[2-(trifluoro... 7 2
Tyrosine-protein kinase JAK2 inhibitor [4-[[5-(1-ethylpyrazol-... 2 3
Cyclin-dependent kinase 1 inhibitor N-[[5-[(3Z)-3-[4-(methoxym... 3 7
Mitogen-activated protein kinase 14 inhibitor ethyl 4-[5-[(3-f... 2 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485388 CHEMBL394057 Bioactive 2-[[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methoxy]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26817 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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