CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28323
Family Name C-C chemokine receptor type 3 ligand 4-[[2-(4-chlorophenyl)ethyl-[1-(2,6-difluorobenzoyl)piperidin-4-yl]amino]methyl]-2-(4-chloropyridin-3-yl)-1,5-dimethylpyrazol-3-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00485392 Functional Category Bioactive
Superfamily C-C chemokine receptor type 3 Binder Superfamily 2
Class Class 840

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Substance-P receptor Ligand TAK-637 Family 18 63
XL-888 family 16 85
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Coagulation factor X inhibitor AGN-PC-075AY8 family 28 21
Hepatocyte growth factor receptor and Insulin receptor ligand ... 4 15
C-X-C chemokine receptor type 3 ligand SureCN13205646 family 4 0
Coagulation factor X and Kallikrein-1 inhibitor SureCN890858 f... 5 6
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 3 2
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Melanin-concentrating hormone receptor 1 ligand 6-(4-chlorophe... 8 1
Coagulation factor X inhibitor 5-bromo-N-(5-chloropyridin-2-yl... 1 1
Coagulation factor X inhibitor AGN-PC-078Y0S family 7 1
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Potassium ... 1 0
C-C chemokine receptor type 3 ligand AGN-PC-046Y2D family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485393 CHEMBL397599 Bioactive 4-[[2-(4-chlorophenyl)ethyl-[1-(2,6-difluorobenzoyl)piperidin-4-yl]amino]methyl]-1,5-dimethyl-2-pyridin-2-ylpyrazol-3-one
CFAMM00485392 CHEMBL394444 Bioactive 4-[[2-(4-chlorophenyl)ethyl-[1-(2,6-difluorobenzoyl)piperidin-4-yl]amino]methyl]-2-(4-chloropyridin-3-yl)-1,5-dimethylpyrazol-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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