CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28325
Family Name Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 1-substituted diazepanone 9g family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00485395 Functional Category Bioactive
Superfamily Calpain-1 catalytic subunit and Cathepsin B Binder Superfamily 2
Class Class 1181

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Cruzipain Inhibitor WRR-204 Family 18 35
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-lle-agly-ile-v... 17 7
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-nal-agly-ile-v... 3 2
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Cathepsin B and Cathepsin S Inhibitor Cbz-ile-leu-ala-leuvsme ... 12 14
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(1-me... 3 8
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 2 2
Neprilysin and Aminopeptidase N inhibitor benzyl 2-[[(2S)-2-[[... 1 1
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl... 4 27
Cathepsin S inhibitor SureCN7397817 family 9 4
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Lethal factor and Cytochrome P450 2D6 inhibitor (2S)-2-[(2R)-2... 10 14
Pol polyprotein inhibitor AC1LADQG family 7 1
Proteasome subunit beta type-5 and Proteasome subunit beta typ... 1 0
Neprilysin inhibitor benzyl (2S)-2-[[2-(sulfanylmethyl)-3,4-di... 4 0
Protease inhibitor AC1O54RX family 2 4
Substance-P receptor and Voltage-dependent L-type calcium chan... 1 0
Solute carrier family 12 member 5 inhibitor AGN-PC-07ZCLM family 1 12
Gamma-secretase subunit PEN-2 inhibitor SureCN5966881 family 1 9
Substance-P receptor ligand (3,5-dimethylphenyl)methyl (2S)-2-... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485395 CHEMBL395004 Bioactive 1-substituted diazepanone 9g

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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