CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28333
Family Name Histamine H3 receptor and Histamine H1 receptor ligand (NE)-N-[1-[4-[[4-(piperidin-1-ylmethyl)phenyl]methoxy]phenyl]ethylidene]hydroxylamine family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00485406 Functional Category Bioactive
Superfamily Alpha adrenergic receptor Ligand Phenoxybenzamine Superfamily
Class Class 280

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Substance-P receptor Ligand Ezlopitant Family 10 207
Dapoxetine family 3 40
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-(4-methoxyphenox... 2 1
Histamine H3 receptor ligand SureCN6071181 family 2 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Sigma non-opioid intracellular receptor 1 ligand 4-[[1-[(2-bro... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Histamine H3 receptor and Histamine H1 receptor ligand AGN-PC-... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485406 CHEMBL39716 Bioactive (NE)-N-[1-[4-[[4-(piperidin-1-ylmethyl)phenyl]methoxy]phenyl]ethylidene]hydroxylamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27619 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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