CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28401
Family Name Mu-type opioid receptor and Kappa-type opioid receptor ligand 1-[[(3S)-2-[[(2R)-1-benzylpyrrolidin-2-yl]methylcarbamothioyl]-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-3-tert-butylurea family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00485566 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 4256

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Substance-P receptor Ligand Orvepitant Family 11 46
Substance-P receptor Ligand Vestipitant Family 14 137
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 11 6
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 1
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 1
Mu-type opioid receptor ligand N-[4-[[(2R)-2-[[[(3S)-3-[(pheny... 1 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485566 CHEMBL40825 Bioactive 1-[[(3S)-2-[[(2R)-1-benzylpyrrolidin-2-yl]methylcarbamothioyl]-3,4-dihydro-1H-isoquinolin-3-yl]methyl]-3-tert-butylurea
CFAMM00485565 CHEMBL41245 Bioactive 1-tert-butyl-3-[[(3S)-2-[[(2R)-pyrrolidin-2-yl]methylcarbamothioyl]-3,4-dihydro-1H-isoquinolin-3-yl]methyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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