CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28419
Family Name Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 inhibitor 4-ethoxy-N-[(2S)-1-oxo-3-phenyl-1-[4-(trifluoromethoxy)anilino]propan-2-yl]-1-(sulfanylmethyl)cyclohexane-1-carboxamide family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00485600 Functional Category Bioactive
Superfamily Renin and Beta-lactamase Binder Superfamily
Class Class 1550

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Substance-K receptor Ligand MEN-14933 Family 13 154
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 9 43
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 11 13
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Cathepsin S and Cathepsin K inhibitor SureCN3018173 family 2 4
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 6 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485600 CHEMBL413270 Bioactive 4-ethoxy-N-[(2S)-1-oxo-3-phenyl-1-[4-(trifluoromethoxy)anilino]propan-2-yl]-1-(sulfanylmethyl)cyclohexane-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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