CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28428
Family Name Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase inhibitor AGN-PC-001R9P family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00485612 Functional Category Bioactive
Superfamily Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Binder Superfamily 4
Class Class 2572

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Histamine H3 receptor Ligand A-349821 Family 49 228
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Aminopeptidase N Inhibitor N1-(3-phenoxybenzyl)-n3-hydroxymalo... 1 5
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Prothrombin inhibitor N-cyclohexyl-3-[3-(diaminomethylideneami... 3 4
Leukotriene B4 receptor 1 ligand AGN-PC-00GEAR family 2 2
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 8
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
Histamine H3 receptor and D(3) dopamine receptor ligand AGN-PC... 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 12
Arachidonate 5-lipoxygenase inhibitor methyl 5-[1-(2-butyl-1-b... 2 4
Neuromedin-K receptor ligand SureCN2478117 family 1 0
Nuclear receptor ROR-gamma ligand 3-(1,3-benzodioxol-5-yl)-1-(... 3 36
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 3
Lysosomal alpha-glucosidase inhibitor MLS000587024 family 1 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN4877195 family 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-02TTXV family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485612 CHEMBL415963 Bioactive AGN-PC-001R9P

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26384 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543