CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28435
Family Name Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha inhibitor 3-[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]phenyl]benzoic acid family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00485629 Functional Category Bioactive
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzylamino)benzoyl]benzoic Acid Superfamily
Class Class 2279

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
Cholecystokinin receptor type A Ligand Gi 181771 Family 3 18
Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Beta-secretase 1 Inhibitor KMI-538 Family 4 20
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Free fatty acid receptor 1 ligand AGN-PC-03ZC6J family 2 14
Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethyl... 1 3
Dihydrofolate reductase inhibitor AGN-PC-073POJ family 1 0
Retinoic acid receptor beta and Retinoic acid receptor gamma l... 4 7
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485629 CHEMBL417600 Bioactive 3-[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]phenyl]benzoic acid
CFAMM00485628 CHEMBL55497 Bioactive 3-[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylphenyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26839 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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