CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28444
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-specific 3',5'-cyclic phosphodiesterase 4C inhibitor AGN-PC-074RRF family
No. of Seeds 4 No. of Other Members 3
Family Centroid CFAMM00485647 Functional Category Bioactive
Superfamily Peptide deformylase, mitochondrial Inhibitor Trimetrexate Superfamily
Class Class 377

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 5 45
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 1 0
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075FPC ... 6 1
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 4 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Vascular endothelial growth factor receptor 2 and Aurora kinas... 4 3
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 7 16
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485648 CHEMBL97214 Bioactive AGN-PC-074RSB
CFAMM00485647 CHEMBL418785 Bioactive AGN-PC-074RRF
CFAMM00485646 CHEMBL98662 Bioactive AGN-PC-074RRK
CFAMM00485645 CHEMBL97817 Bioactive 2-[4-[3,5-bis(cyclopropylmethoxy)phenyl]-2-ethyl-6-methoxyquinazolin-7-yl]oxyethanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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