CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28458
Family Name Corticotropin-releasing factor receptor 1 and Corticotropin-releasing factor receptor 2 ligand 4-(2,4-dichlorophenyl)-5-methyl-N-propyl-N-quinolin-5-yl-1,3-thiazol-2-amine family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00485682 Functional Category Bioactive
Superfamily Histamine H3 receptor and Survival motor neuron protein Binder Superfamily
Class Class 2616

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZXHN fa... 2 4
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M88D fa... 2 1
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 5-[5-chloro-... 2 18
Transient receptor potential cation channel subfamily V member... 9 13


External ID

Functional Category

Molecule Name

CFAMM00485682 CHEMBL42073 Bioactive 4-(2,4-dichlorophenyl)-5-methyl-N-propyl-N-quinolin-5-yl-1,3-thiazol-2-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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