CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28466
Family Name Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor 5-[(3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carbonyl]oxypentyl (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00485697 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-(3-chlorobenzyl)methylphenidate Superfamily
Class Class 187

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent serotonin transporter inhibitor CHEMBL265808 ... 1 0
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Transporter and Sodium-dependent dopamine transporter inhibito... 1 5
Sodium-dependent dopamine transporter and Transporter inhibito... 1 1
Sodium- and chloride-dependent GABA transporter 1 inhibitor Su... 8 8
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0


External ID

Functional Category

Molecule Name

CFAMM00485697 CHEMBL42203 Bioactive 5-[(3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carbonyl]oxypentyl (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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