CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28473
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-074LG7 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00485714 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 21
Class Class 72

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Farnesyltransferase beta subunit, putative Inhibitor Lonafarni... 36 87
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 10 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Coagulation factor X inhibitor 3-(6-chloronaphthalen-2-yl)sulf... 5 10
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485714 CHEMBL423677 Bioactive AGN-PC-074LG7
CFAMM00485713 CHEMBL430450 Bioactive AGN-PC-040RMO

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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