CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28484
Family Name Endothelin-converting enzyme 1 and Angiotensin-converting enzyme inhibitor (4R)-N'-methyl-N'-(4-methylphenyl)sulfonyl-1-naphthalen-2-ylsulfonyl-4-sulfanylpyrrolidine-2-carbohydrazide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00485746 Functional Category Bioactive
Superfamily Cathepsin B and Prothrombin Binder Superfamily
Class Class 3217

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 6 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 1
Disintegrin and metalloproteinase domain-containing protein 17... 6 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
Neutrophil collagenase and Collagenase 3 inhibitor (2R)-2-[2-a... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485746 CHEMBL425383 Bioactive (4R)-N'-methyl-N'-(4-methylphenyl)sulfonyl-1-naphthalen-2-ylsulfonyl-4-sulfanylpyrrolidine-2-carbohydrazide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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