CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28525
Family Name Renin inhibitor (4S,5S,7S)-5-amino-N-butyl-7-[[4-tert-butyl-3-(methylsulfonylmethoxy)phenyl]methyl]-4-hydroxy-2,8-dimethylnonanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00485868 Functional Category Bioactive
Superfamily Renin Inhibitor Aliskiren Superfamily
Class Class 609

Cousin Family NamesSeedsMembers
Renin Inhibitor Aliskiren Family 28 107
Substance-P receptor Ligand DA-5018 Family 14 73
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Renin inhibitor N-[(2S,4S,5S,7S)-7-[2-(1-acetylpiperidin-4-yl)... 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (5Z,8... 4 2
Renin inhibitor (2S,4S,5S,7S)-5-amino-4-hydroxy-7-[[4-methoxy-... 2 0
Renin inhibitor N-[(2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy... 5 1


External ID

Functional Category

Molecule Name

CFAMM00485868 CHEMBL433218 Bioactive (4S,5S,7S)-5-amino-N-butyl-7-[[4-tert-butyl-3-(methylsulfonylmethoxy)phenyl]methyl]-4-hydroxy-2,8-dimethylnonanamide
CFAMM00485866 CHEMBL557369 Bioactive (2R,4S,5S,7S)-5-amino-N-butyl-7-[[4-tert-butyl-3-(methylsulfonylmethoxy)phenyl]methyl]-4-hydroxy-2,8-dimethylnonanamide;hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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