CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28554
Family Name Receptor tyrosine-protein kinase erbB-2 and Insulin-like growth factor 1 receptor ligand AGN-PC-050GRY family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00485926 Functional Category Bioactive
Superfamily Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase erbB-2 Binder Superfamily
Class Class 855

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor Birb 796 Family 20 43
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 4 32
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 24 79
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 10
Tyrosine-protein kinase ABL1 and Tyrosine-protein kinase HCK i... 2 2
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Mitogen-activated protein kinase 10 and Transcription factor A... 4 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
ALK tyrosine kinase receptor and Nucleophosmin ligand N-[2-met... 8 1
Vascular endothelial growth factor receptor 1 and Fibroblast g... 3 7
ALK tyrosine kinase receptor and Nucleophosmin ligand N-[2-[2-... 5 0
TGF-beta receptor type-2 and Vascular endothelial growth facto... 2 1
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 16 7
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 0
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Aurora kinase B and Aurora kinase A inhibitor 1-cyclohexyl-3-[... 4 0
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 0
Insulin-like growth factor 1 receptor ligand SureCN2967184 family 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00485929 CHEMBL452717 Bioactive AGN-PC-050GRW
CFAMM00485927 CHEMBL446250 Bioactive SureCN2959387
CFAMM00485926 CHEMBL448628 Bioactive AGN-PC-050GRY
CFAMM00485931 CHEMBL437584 Bioactive AGN-PC-050GRU

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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