CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM28634
Family Name Orexin receptor type 1 and Orexin receptor type 2 ligand SureCN4425867 family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00486227 Functional Category Bioactive with Natural Product
Superfamily Beta-secretase 1 and Beta-secretase 2 Binder Superfamily 4
Class Class 513

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Gonadotropin-releasing hormone receptor ligand 1-[(2,6-difluor... 6 31
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17i ... 3 6
Nitric oxide synthase, inducible inhibitor SureCN5194847 family 24 48
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00486227 CHEMBL451281 Bioactive SureCN4425867

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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